Publications A composite disease activity index for early drug development in ulcerative colitis: development and validation of the UC-100 score Citation Jairath V, Jeyarajah J, Zou G, Parker CE, Olson A, Khanna R, D'Haens GR, Sandborn WJ, Feagan BG. A composite disease activity index for early drug development in ulcerative colitis: development and validation of the UC-100 score. Lancet Gastroenterol Hepatol. 2019 Jan;4(1):63-70. doi: 10.1016/S2468-1253(18)30306-6. Epub 2018 Oct 18. PMID: 30343116. Abstract Background: Combining clinical, endoscopic, and histological data associated with ulcerative colitis disease activity in a composite index could be a more sensitive way to detect efficacy in small numbers of patients during early drug development. Our aim was to derive and externally validate a novel index for this purpose. Tags Complications, Diagnosis, Drug Development, Drug Therapy, Endoscopy, Etiology, Gastrointestinal Hemorrhage, Pathology, Ulcerative Colitis Read More
