Publications Disease activity indices in coeliac disease: systematic review and recommendations for clinical trials Citation Hindryckx P, Levesque BG, Holvoet T, Durand S, Tang CM, Parker C, Khanna R, Shackelton LM, D'Haens G, Sandborn WJ, Feagan BG, Lebwohl B, Leffler DA, Jairath V. Disease activity indices in coeliac disease: systematic review and recommendations for clinical trials. Gut. 2018 Jan;67(1):61-69. doi: 10.1136/gutjnl-2016-312762. Epub 2016 Oct 31. PMID: 27799282. Abstract Objective: Although several pharmacological agents have emerged as potential adjunctive therapies to a gluten-free diet for coeliac disease, there is currently no widely accepted measure of disease activity used in clinical trials. We conducted a systematic review of coeliac disease activity indices to evaluate their operating properties and potential as outcome measures in registration trials. Tags Biomarker, Celiac Disease, Clinical Trials, COELIAC DISEASE, Diagnosis, Endoscopy, Gastrointestinal, GLUTEN SENSITIVE ENTEROPATHY, Outcome Assessment, Pathology, Therapy Read More